Development of the OAB-q

Given the high prevalence and substantial negative impact of OAB, reliable and well validated measures are needed to assess treatment outcomes on patients' quality of life. Because OAB is defined by symptoms, patient-reported outcome measures (PROs) are essential for complete assessment of these symptoms and their impact.

  1. Based on focus groups with male and female OAB patients as well as literature review, 66 initial items were generated for the OAB-q.

  2. Content validity of these items was assessed through interviews with clinical experts and cognitive debriefing with OAB patients.

  3. Through item and factor analysis, the initial pool of 66 items was reduced to the final 33-item questionnaire. (Coyne et al. 2002)
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